Transfusion Support for Xenotransplantation

Saturday, October 19, 2024

11:15 AM - 12:15 PM

Location: 362

CE: 1 CME (AMA Physician Credit) / 1 CE (Non-Physician Credit)

Speaker(s)

Victoria Costa, MD (she/her/hers)

Assistant Medical Director
NYU Langone Health, New York, United States

Disclosure(s): No financial relationships to disclose

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Program Chair(s)

Timothy Hilbert, MD PhD JD

Medical Director
NYU Langone Health
New York, New York, United States

Disclosure(s): No financial relationships to disclose

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Speaker(s)

Massimo Mangiola, PhD

Immunogenetics Laboratory Director at Transplant Institute
NYU Langone Health
New York, New York, United States

Disclosure(s): No financial relationships to disclose

PDF

Disclosure(s):

Victoria Costa, MD: No financial relationships to disclose

Timothy Hilbert, MD PhD JD: No financial relationships to disclose

Massimo Mangiola, PhD: No financial relationships to disclose

Session Desription: We will share our experience performing xenotransplantation (transplantation of genetically modified pig kidneys into human bodies) and the role of xenotransplantation in the search for new sources of viable organs for people facing life-threatening diseases. The transplant team will review the context and process of xenotransplantation, including histocompatibility testing, and discuss the findings and remaining questions from recent cases. The transfusion medicine team will discuss transfusion needs in this patient population and the approach to providing transfusion support.

Learning Objectives:

Describe the organ donation process and the concept of xenotransplantation.
Describe histocompatibility testing and demonstrate that human blood products contain clinically significant anti-pig antibodies.
Describe outcomes of recent xenotransplantation studies.
Describe approach to providing transfusion support.
Describe use of medical intervention to prevent organ rejection.